Generic name


Covered by Medicare


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Average Annual Cost per Beneficiary


Average cost per year*

Average Annual Cost per Dose



Average cost per beneficiary*


  • Tolmar Inc.
  • Gsms, Inc.
  • Xiromed, LLC
  • Perrigo/Padagis
  • Hi-Tech/Akorn C
  • Zydus Pharmaceu*
  • Ranbaxy Pharmac
  • Northstar Rx Ll
  • Teva USA*
  • Viona Pharmaceu*
  • Taro Pharm USA
  • Yiling Pharmace
  • Mylan*
  • Torrent Pharmac
  • Ranbaxy/Sun Pha
  • Nivagen Pharmac
  • Novitium Pharma
  • Alembic Pharmac
  • Cosette Pharmac
  • Glenmark Pharma
  • Avet Pharmaceut
  • Camber Pharmace
  • Actavis/Teva*
  • Carlsbad Tech
  • Fougera/Sandoz
  • Apotex Corp
  • AHP
  • Bionpharma Inc.
  • Major Pharmaceu
  • Amneal Pharmace
  • Quinn Pharmaceu
  • Mylan Instituti

What is Acyclovir

Acyclovir is used to treat infections caused by certain types of viruses. It treats cold sores around the mouth (caused by herpes simplex), shingles (caused by herpes zoster), and chickenpox. This medication is also used to treat outbreaks of genital herpes. In people with frequent outbreaks, acyclovir is used to help reduce the number of future episodes. Acyclovir is an antiviral drug. However, it is not a cure for these infections. The viruses that cause these infections continue to live in the body even between outbreaks. Acyclovir decreases the severity and length of these outbreaks. It helps the sores heal faster, keeps new sores from forming, and decreases pain/itching. This medication may also help reduce how long pain remains after the sores heal. In addition, in people with a weakened immune system, acyclovir can decrease the risk of the virus spreading to other parts of the body and causing serious infections. NOTE: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.

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*Origin of the terms and chart data used within this page:

Common Questions About Acyclovir

Yes, Acyclovir is covered by Medicare.

In 2021, the average cost per dose of Acyclovir was $1.33.

The average dose of Acyclovir received per year is 128,736,538 units

660,087 Medicare beneficiaries received Acyclovir in 2021, which was a -0.01% from 2020

There were 1,827,373 claims made by Medicare beneficiaries, which is a -0.03% from 2020

The average spending amount per claim in 2021 was $29.91

The average Medicare spending per beneficiary amount for Acyclovir was $82.79

The most expensive manufacturer of Acyclovir is Perrigo/Padagis

Nivagen Pharmac is the least expensive manufacturer with an Average Spending Per Dosage Unit of $0.11

Camber Pharmace received $15,665,296.46

The total amount spent on Acyclovir by Medicare is $54,649,405.19

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