Generic name


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Average Annual Cost per Beneficiary


Average cost per year*

Average Annual Cost per Dose



Average cost per beneficiary*


  • Wockhardt USA L
  • Sun Pharma Glob
  • Sandoz
  • Mylan

What is Carbidopa-Levodopa-Entacapone

This combination medication is used to treat symptoms of Parkinson's disease (such as shakiness, stiffness, difficulty moving). Parkinson's disease is thought to be caused by too little of a naturally occurring substance (dopamine) in the brain. Levodopa changes into dopamine in the brain, helping to control movement. Carbidopa and entacapone prevent the breakdown of levodopa in the bloodstream so more levodopa can enter the brain. Carbidopa can also reduce some of levodopa's side effects such as nausea and vomiting. NOTE: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.

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*Origin of the terms and chart data used within this page:

Common Questions About Carbidopa-Levodopa-Entacapone

Yes, Carbidopa-Levodopa-Entacapone is covered by Medicare.

In 2021, the average cost per dose of Carbidopa-Levodopa-Entacapone was $1.96.

The average dose of Carbidopa-Levodopa-Entacapone received per year is 13,448,117 units

10,936 Medicare beneficiaries received Carbidopa-Levodopa-Entacapone in 2021, which was a -0.1% from 2020

There were 63,591 claims made by Medicare beneficiaries, which is a -0.17% from 2020

The average spending amount per claim in 2021 was $330.33

The average Medicare spending per beneficiary amount for Carbidopa-Levodopa-Entacapone was $1,920.81

The most expensive manufacturer of Carbidopa-Levodopa-Entacapone is Sun Pharma Glob

Mylan is the least expensive manufacturer with an Average Spending Per Dosage Unit of $1.87

Sandoz received $17,099,237.58

The total amount spent on Carbidopa-Levodopa-Entacapone by Medicare is $21,005,926.97

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