Generic name

Methylprednisolone Acetate

Covered by Medicare


Get a Medicare Quote

Average Annual Cost per Beneficiary


Average cost per year*

Average Annual Cost per Dose



Average cost per beneficiary*


  • Pharmaci/Pfizer
  • Pfizer/Novaplus

What is Depo-Medrol

Methylprednisolone is used to treat pain and swelling that occurs with arthritis and other joint disorders. This medication may also be used to treat various conditions such as blood disorders, severe allergic reactions, certain cancers, eye conditions, skin/intestinal/kidney/lung diseases, and immune system disorders. It decreases your immune system's response to these conditions and reduces symptoms such as swelling, pain, and allergic-type reactions. Talk to your doctor about the risks and benefits of methylprednisolone, especially if it is to be injected near your spine (epidural). Rare but serious side effects may occur with epidural use. Methylprednisolone is a corticosteroid hormone. Methylprednisolone may also be used with other medications in hormone disorders. NOTE: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.

Drug Trends

*Origin of the terms and chart data used within this page:

Common Questions About Depo-Medrol

Yes, Depo-Medrol is covered by Medicare.

In 2021, the average cost per dose of Depo-Medrol was $15.15.

The average dose of Depo-Medrol received per year is 8,122 units

861 Medicare beneficiaries received Depo-Medrol in 2021, which was a -0.43% from 2020

There were 1,054 claims made by Medicare beneficiaries, which is a -0.45% from 2020

The average spending amount per claim in 2021 was $27.21

The average Medicare spending per beneficiary amount for Depo-Medrol was $33.31

The most expensive manufacturer of Depo-Medrol is Pfizer/Novaplus

Pharmaci/Pfizer is the least expensive manufacturer with an Average Spending Per Dosage Unit of $14.86

Pharmaci/Pfizer received $26,289.50

The total amount spent on Depo-Medrol by Medicare is $28,677.19

© 2021-2024, LLC

Privacy Policy  |  Terms and Conditions

GENERAL DISCLAIMERS is a commercial site designed for the solicitation of insurance from selected health insurance carriers and, LLC is a licensed insurance agency. It is not a government agency. It is also not an insurer, or a medical provider., LLC is a licensed representative of Medicare Advantage (HMO, PPO, PFFS, and PDP) organizations that have a Medicare contract. Enrollment depends on the plan’s contract renewal.
We do not offer every plan available in your area. Currently we represent nine carrier plan organizations nationally. Please contact, 1-800-MEDICARE, or your local State Health Insurance Program (SHIP) to get information on all of your options.
Alternatively, you may be referred, via a link, to a selected partner website, which is independently owned and operated and may have different privacy and terms of use policies from us.
If you provide your contact information to us, an insurance agent/producer or insurance company may contact you. If you do not speak English, language assistance service, free of charge, is available to you; contact the toll-free number listed above. This site is not maintained by or affiliated with the federal government's Health Insurance Marketplace website or any state government health insurance marketplace.
The plans we represent do not discriminate on the basis of race, color, national origin, age, disability, or sex. To learn more about a plan's nondiscrimination policy, please click here.
Not all plans offer all of these benefits. Benefits may vary by carrier and location. Limitations and exclusions may apply.