Generic name


Covered by Medicare


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Average Annual Cost per Beneficiary


Average cost per year*

Average Annual Cost per Dose



Average cost per beneficiary*


  • Specgx LLC
  • Mylan
  • Mallinckrodt Ph
  • Apotex/Novaplus
  • Apotex Corp
  • Alvogen Inc

What is Fentanyl

This medication is used to help relieve severe ongoing pain (such as due to cancer). Fentanyl belongs to a class of drugs known as opioid analgesics. It works in the brain to change how your body feels and responds to pain. Do not use the patch form of fentanyl to relieve pain that is mild or that will go away in a few days. This medication is not for occasional ("as needed") use. NOTE: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.

Drug Trends

*Origin of the terms and chart data used within this page: https://data.cms.gov/

Common Questions About Fentanyl

Yes, Fentanyl is covered by Medicare.

In 2021, the average cost per dose of Fentanyl was $9.92.

The average dose of Fentanyl received per year is 16,259,164 units

156,332 Medicare beneficiaries received Fentanyl in 2021, which was a -0.11% from 2020

There were 1,185,996 claims made by Medicare beneficiaries, which is a -0.14% from 2020

The average spending amount per claim in 2021 was $101.20

The average Medicare spending per beneficiary amount for Fentanyl was $767.77

The most expensive manufacturer of Fentanyl is Specgx LLC

Apotex/Novaplus is the least expensive manufacturer with an Average Spending Per Dosage Unit of $7.50

Mylan received $41,814,355.63

The total amount spent on Fentanyl by Medicare is $120,027,255.95

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