Generic name


Covered by Medicare


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Average Annual Cost per Beneficiary


Average cost per year*

Average Annual Cost per Dose



Average cost per beneficiary*


  • Zydus Pharmaceu
  • Winthrop US
  • Lupin Pharmaceu
  • KVK-Tech, Inc.
  • Avkare
  • Avet Pharmaceut
  • Aurobindo Pharm
  • Apotex Corp
  • Alembic Pharmac

What is Leflunomide

This medication is used to treat rheumatoid arthritis, a condition in which the body's defense system (immune system) fails to recognize the body as itself and attacks the healthy tissues around the joints. Leflunomide helps to reduce the joint damage/pain/swelling and helps you to move better. It works by weakening your immune system and decreasing swelling (inflammation). NOTE: This is a summary and does NOT have all possible information about this product. This information does not assure that this product is safe, effective, or appropriate for you. This information is not individual medical advice and does not substitute for the advice of your health care professional. Always ask your health care professional for complete information about this product and your specific health needs.

Drug Trends

*Origin of the terms and chart data used within this page: https://data.cms.gov/

Common Questions About Leflunomide

Yes, Leflunomide is covered by Medicare.

In 2021, the average cost per dose of Leflunomide was $2.04.

The average dose of Leflunomide received per year is 24,159,445 units

120,965 Medicare beneficiaries received Leflunomide in 2021, which was a 0.07% from 2020

There were 496,397 claims made by Medicare beneficiaries, which is a 0.01% from 2020

The average spending amount per claim in 2021 was $114.37

The average Medicare spending per beneficiary amount for Leflunomide was $469.33

The most expensive manufacturer of Leflunomide is Alembic Pharmac

Avet Pharmaceut is the least expensive manufacturer with an Average Spending Per Dosage Unit of $1.53

Apotex Corp received $13,080,366.46

The total amount spent on Leflunomide by Medicare is $56,772,608.94

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